Add Blocked File Types in SharePoint 2010
string webAppUrl = "Your URL" ; string myBlockFileType = "dll" ; Uri myUri = new Uri (webAppUrl); SPWebApplication myWebApp = SPWebApplication .Lookup(myUri); Collection< string > blockFileTypes = myWebApp.BlockedFileExtensions; blockFileTypes.Add(myBlockFileType); myWebApp.Update(); Hope this will helps ...